Изучение механизмов ограничения активности энхансеров D. melanogaster

выводы.

1) Показано, что некодирующая транскрипция негативно влияет на активность энхансеров генов white и yellow.

2) Продемонстрировано, что терминаторы транскрипции стабилизируют функционирование энхансеров генов white и yellow в составе трансгенов.

3) Установлено, что 1А2- и Wari-инсуляторы функционально взаимодействуют с промоторами разных классов.

4) Выяснено, что обогащение белков CP 190 и Mod (mdg4)-67.2 на промоторе гена even-skipped зависит от присутствия 1 А2-инсулятора в трансгене.

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