Π”ΠΈΠΏΠ»ΠΎΠΌ, курсовая, ΠΊΠΎΠ½Ρ‚Ρ€ΠΎΠ»ΡŒΠ½Π°Ρ Ρ€Π°Π±ΠΎΡ‚Π°
ΠŸΠΎΠΌΠΎΡ‰ΡŒ Π² написании студСнчСских Ρ€Π°Π±ΠΎΡ‚

Π‘ΠΎΡ‡Π΅Ρ‚Π°Π½ΠΈΠ΅ хроничСской сСрдСчной нСдостаточности ΠΈ сахарного Π΄ΠΈΠ°Π±Π΅Ρ‚Π° 2-Π³ΠΎ Ρ‚ΠΈΠΏΠ°: общая характСристика Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ…, клиничСская ΠΊΠ°Ρ€Ρ‚ΠΈΠ½Π°, ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΡ‹ лСчСния ΠΈ ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·Π°

Π”ΠΈΡΡΠ΅Ρ€Ρ‚Π°Ρ†ΠΈΡΠŸΠΎΠΌΠΎΡ‰ΡŒ Π² Π½Π°ΠΏΠΈΡΠ°Π½ΠΈΠΈΠ£Π·Π½Π°Ρ‚ΡŒ ΡΡ‚ΠΎΠΈΠΌΠΎΡΡ‚ΡŒΠΌΠΎΠ΅ΠΉ Ρ€Π°Π±ΠΎΡ‚Ρ‹

ΠŸΠ°Ρ†ΠΈΠ΅Π½Ρ‚Ρ‹ с ΡΠΎΡ‡Π΅Ρ‚Π°Π½ΠΈΠ΅ΠΌ Π₯БН ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° ΠΈΠΌΠ΅ΡŽΡ‚ Π½Π΅ Ρ‚ΠΎΠ»ΡŒΠΊΠΎ Π±ΠΎΠ»Π΅Π΅ высокий ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ Π³Π»ΠΈΠΊΠ΅ΠΌΠΈΠΈ ΠΈ Ρ‡Π°ΡΡ‚ΠΎΡ‚Ρƒ Π³Π»ΡŽΠΊΠΎΠ·ΡƒΡ€ΠΈΠΈ, Π½ΠΎ ΠΈ ΡΠΊΠ»ΠΎΠ½Π½ΠΎΡΡ‚ΡŒ ΠΊ ΠΎΠΆΠΈΡ€Π΅Π½ΠΈΡŽ (достовСрно ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½Π½Ρ‹ΠΉ ИМВ) ΠΈ Π½Π°Ρ€ΡƒΡˆΠ΅Π½ΠΈΡŽ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ ΠΏΠΎΡ‡Π΅ΠΊ, Ρ‡Ρ‚ΠΎ характСризуСтся ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½Π½Ρ‹ΠΌ ΡƒΡ€ΠΎΠ²Π½Π΅ΠΌ ΠΊΡ€Π΅Π°Ρ‚ΠΈΠ½ΠΈΠ½Π° ΠΈ ΠΌΠΈΠΊΡ€ΠΎΠ°Π»ΡŒΠ±ΡƒΠΌΠΈΠ½ΡƒΡ€ΠΈΠΈ, Ρ‚. Π΅. сама Π₯БН Π½Π΅ «ΠΌΠ°ΡΠΊΠΈΡ€ΡƒΠ΅Ρ‚» клиничСских ΠΈ Π»Π°Π±ΠΎΡ€Π°Ρ‚ΠΎΡ€Π½Ρ‹Ρ… проявлСний Π‘Π” 2 Ρ‚ΠΈΠΏΠ°, Π° Π² Π½Π°Ρ€ΡƒΡˆΠ΅Π½ΠΈΠ΅ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ ΠΏΠΎΡ‡Π΅ΠΊ вносят Π²ΠΊΠ»Π°Π΄ ΠΎΠ±Π° ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½Ρ‚Π°… Π§ΠΈΡ‚Π°Ρ‚ΡŒ Π΅Ρ‰Ρ‘ >

Π‘ΠΎΠ΄Π΅Ρ€ΠΆΠ°Π½ΠΈΠ΅

  • УсловныС обозначСния

Π‘ΠΎΡ‡Π΅Ρ‚Π°Π½ΠΈΠ΅ хроничСской сСрдСчной нСдостаточности ΠΈ сахарного Π΄ΠΈΠ°Π±Π΅Ρ‚Π° 2-Π³ΠΎ Ρ‚ΠΈΠΏΠ°: общая характСристика Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ…, клиничСская ΠΊΠ°Ρ€Ρ‚ΠΈΠ½Π°, ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΡ‹ лСчСния ΠΈ ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·Π° (Ρ€Π΅Ρ„Π΅Ρ€Π°Ρ‚, курсовая, Π΄ΠΈΠΏΠ»ΠΎΠΌ, ΠΊΠΎΠ½Ρ‚Ρ€ΠΎΠ»ΡŒΠ½Π°Ρ)

ЦСль исслСдования. 8.

Π—Π°Π΄Π°Ρ‡ΠΈ исслСдования. 8.

Научная Π½ΠΎΠ²ΠΈΠ·Π½Π°.8.

ΠŸΡ€Π°ΠΊΡ‚ΠΈΡ‡Π΅ΡΠΊΠ°Ρ Π·Π½Π°Ρ‡ΠΈΠΌΠΎΡΡ‚ΡŒ.10.

ΠžΡΠ½ΠΎΠ²Π½Ρ‹Π΅ полоТСния, выносимыС Π½Π° Π·Π°Ρ‰ΠΈΡ‚Ρƒ.10.

Π’Π½Π΅Π΄Ρ€Π΅Π½ΠΈΠ΅ Π² ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊΡƒ.11.

ΠšΠΎΠ»ΠΈΡ‡Π΅ΡΡ‚Π²ΠΎ ΠΎΠΏΡƒΠ±Π»ΠΈΠΊΠΎΠ²Π°Π½Π½Ρ‹Ρ… Ρ€Π°Π±ΠΎΡ‚ ΠΈ ΡΠΎΠΎΠ±Ρ‰Π΅Π½ΠΈΠΉ ΠΏΠΎ Ρ‚Π΅ΠΌΠ΅ диссСртации. 11.

Π²Ρ‹Π²ΠΎΠ΄Ρ‹.

1. ΠžΡΠ½ΠΎΠ²Π½Ρ‹ΠΌΠΈ характСристиками ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с ΡΠΎΡ‡Π΅Ρ‚Π°Π½ΠΈΠ΅ΠΌ Π₯БН ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ°, Π² ΡΡ€Π°Π²Π½Π΅Π½ΠΈΠΈ с Π±ΠΎΠ»ΡŒΠ½Ρ‹ΠΌΠΈ с Π₯БН, ΠΏΠΎ Π΄Π°Π½Π½Ρ‹ΠΌ ΠΊΠ°ΠΊ ΠΏΡ€ΠΎ-, Ρ‚Π°ΠΊ ΠΈ Ρ€Π΅Ρ‚роспСктивного исслСдований ΡΠ²Π»ΡΡŽΡ‚ΡΡ: ΠΏΠΎΠΆΠΈΠ»ΠΎΠΉ возраст, ТСнский ΠΏΠΎΠ», Π° Π³ Ρ‚Π°ΠΊΠΆΠ΅ достовСрно Π±ΠΎΠ»Π΅Π΅ частая Π²ΡΡ‚Ρ€Π΅Ρ‡Π°Π΅ΠΌΠΎΡΡ‚ΡŒ Π˜Π‘Π‘ (ΠΈ ΠΏΠΎΡΡ‚ΠΈΠ½Ρ„Π°Ρ€ΠΊΡ‚Π½ΠΎΠ³ΠΎ кардиосклСроза) ΠΈ ΠΠ“, Π² ΠΊΠ°Ρ‡Π΅ΡΡ‚Π²Π΅ Π³Π»Π°Π²Π½Ρ‹Ρ… этиологичСских ΠΏΡ€ΠΈΡ‡ΠΈΠ½ дСкомпСнсации. Π‘ΠΎΠ»Π΅Π΅ часто сохраняСтся синусовый Ρ€ΠΈΡ‚ΠΌ.

2. ΠŸΡ€ΠΈΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΠ΅ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° ΠΊ Π₯БН лишь ΡƒΠ²Π΅Π»ΠΈΡ‡ΠΈΠ²Π°Π΅Ρ‚ ΡΡ‚Π΅ΠΏΠ΅Π½ΡŒ дСкомпСнсации (ΠΏΡ€ΠΎΡ†Π΅Π½Ρ‚ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… с III Π€Πš увСличиваСтся с 49,5% Π΄ΠΎ 73,2%) ΠΈ Π½Π΅ ΠΎΠΊΠ°Π·Ρ‹Π²Π°Π΅Ρ‚ Π·Π½Π°Ρ‡ΠΈΠΌΠΎΠ³ΠΎ влияния Π½ΠΈ Π½Π° ΡΠΈΡΡ‚ΠΎΠ»ΠΈΡ‡Π΅ΡΠΊΡƒΡŽ, Π½ΠΈ Π½Π° Π΄ΠΈΠ°ΡΡ‚ΠΎΠ»ΠΈΡ‡Π΅-ΡΠΊΡƒΡŽ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΡŽ Π›Π–, хотя качСство ΠΆΠΈΠ·Π½ΠΈ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² ΠΏΡ€ΠΈ сочСтании Π₯БН ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° достовСрно ΡƒΡ…ΡƒΠ΄ΡˆΠ°Π΅Ρ‚ΡΡ Π² ΡΡ€Π°Π²Π½Π΅Π½ΠΈΠΈ с Π±ΠΎΠ»ΡŒΠ½Ρ‹ΠΌΠΈ с «ΠΈΠ·ΠΎΠ»ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠΉ» Π₯БН.

3. Π”Π»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ Π΄ΠΈΠ°Π±Π΅Ρ‚Π° Π±ΠΎΠ»Π΅Π΅ 10 Π»Π΅Ρ‚ максимально ΡƒΡ…ΡƒΠ΄ΡˆΠ°Π΅Ρ‚ клиничСскоС Ρ‚Π΅Ρ‡Π΅Π½ΠΈΠ΅ Π±ΠΎΠ»Π΅Π·Π½ΠΈ Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с Π₯БН ΠΈ ΠΏΡ€ΠΈΠ²ΠΎΠ΄ΠΈΡ‚ ΠΊ ΠΏΠΎΡ€Π°ΠΆΠ΅Π½ΠΈΡŽ ΠΎΡ€Π³Π°Π½ΠΎΠ² — мишСнСй (сСрдца, ΠΏΠΎΡ‡Π΅ΠΊ). ΠŸΡ€ΠΈ этом максимально возрастаСт Ρ€ΠΎΠ»ΡŒ ΠΏΡ€ΠΈΡΠΎΠ΅Π΄ΠΈΠ½ΠΈΠ²ΡˆΠ΅ΠΉΡΡ ΠΠ“ ΠΈ ΠΏΠΎΠ΄ΡŠΠ΅ΠΌΠΎΠ² АД, Π½Π°Ρ‡ΠΈΠ½Π°Π΅Ρ‚ ΡΠ½ΠΈΠΆΠ°Ρ‚ΡŒΡΡ систоличСская функция сСрдца ΠΈ Π΄ΠΎΡΡ‚ΠΎΠ²Π΅Ρ€Π½ΠΎ ΠΏΠΎΠ²Ρ‹ΡˆΠ°Π΅Ρ‚ΡΡ ΡΡ‚Π΅ΠΏΠ΅Π½ΡŒ Π°Π»ΡŒΠ±ΡƒΠΌΠΈΠ½ΡƒΡ€ΠΈΠΈ, Ρ‚. Π΅. ΡƒΡ…ΡƒΠ΄ΡˆΠ°Π΅Ρ‚ΡΡ функция ΠΏΠΎΡ‡Π΅ΠΊ. Волько Π΄Π»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎ ΡΡƒΡ‰Π΅ΡΡ‚Π²ΡƒΡŽΡ‰ΠΈΠΉ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° Ρ€Π΅Π°Π»ΡŒΠ½ΠΎ ΡƒΡ…ΡƒΠ΄ΡˆΠ°Π΅Ρ‚ клиничСскоС Ρ‚Π΅Ρ‡Π΅Π½ΠΈΠ΅ Π₯БН.

4. ΠŸΠ°Ρ†ΠΈΠ΅Π½Ρ‚Ρ‹ с ΡΠΎΡ‡Π΅Ρ‚Π°Π½ΠΈΠ΅ΠΌ Π₯БН ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° ΠΈΠΌΠ΅ΡŽΡ‚ Π½Π΅ Ρ‚ΠΎΠ»ΡŒΠΊΠΎ Π±ΠΎΠ»Π΅Π΅ высокий ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ Π³Π»ΠΈΠΊΠ΅ΠΌΠΈΠΈ ΠΈ Ρ‡Π°ΡΡ‚ΠΎΡ‚Ρƒ Π³Π»ΡŽΠΊΠΎΠ·ΡƒΡ€ΠΈΠΈ, Π½ΠΎ ΠΈ ΡΠΊΠ»ΠΎΠ½Π½ΠΎΡΡ‚ΡŒ ΠΊ ΠΎΠΆΠΈΡ€Π΅Π½ΠΈΡŽ (достовСрно ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½Π½Ρ‹ΠΉ ИМВ) ΠΈ Π½Π°Ρ€ΡƒΡˆΠ΅Π½ΠΈΡŽ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ ΠΏΠΎΡ‡Π΅ΠΊ, Ρ‡Ρ‚ΠΎ характСризуСтся ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½Π½Ρ‹ΠΌ ΡƒΡ€ΠΎΠ²Π½Π΅ΠΌ ΠΊΡ€Π΅Π°Ρ‚ΠΈΠ½ΠΈΠ½Π° ΠΈ ΠΌΠΈΠΊΡ€ΠΎΠ°Π»ΡŒΠ±ΡƒΠΌΠΈΠ½ΡƒΡ€ΠΈΠΈ, Ρ‚. Π΅. сама Π₯БН Π½Π΅ «ΠΌΠ°ΡΠΊΠΈΡ€ΡƒΠ΅Ρ‚» клиничСских ΠΈ Π»Π°Π±ΠΎΡ€Π°Ρ‚ΠΎΡ€Π½Ρ‹Ρ… проявлСний Π‘Π” 2 Ρ‚ΠΈΠΏΠ°, Π° Π² Π½Π°Ρ€ΡƒΡˆΠ΅Π½ΠΈΠ΅ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ ΠΏΠΎΡ‡Π΅ΠΊ вносят Π²ΠΊΠ»Π°Π΄ ΠΎΠ±Π° ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½Ρ‚Π° сочСтанной ΠΏΠ°Ρ‚ΠΎΠ»ΠΎΠ³ΠΈΠΈ.

5. НСсмотря Π½Π° Ρ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€Π½ΠΎΠ΅ для Π₯БН Π½Π°Ρ€ΡƒΡˆΠ΅Π½ΠΈΠ΅ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ ΠΏΠ΅Ρ‡Π΅Π½ΠΈ (Π² Ρ‚ΠΎΠΌ числС способности ΠΊ ΡΠΈΠ½Ρ‚Π΅Π·Ρƒ холСстСрина), ΠΏΡ€ΠΈ сочСтании дСкомпСнсации с Π‘Π” 2 Ρ‚ΠΈΠΏΠ° ΠΏΡ€ΠΎΡΠ²Π»ΡΡŽΡ‚ΡΡ Ρ‚ΠΈΠΏΠΈΡ‡Π½Ρ‹Π΅ Ρ‡Π΅Ρ€Ρ‚Ρ‹ диабСтичСской дислипидСмии Π² Π²ΠΈΠ΄Π΅ ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½ΠΈΡ Ρ‚Ρ€ΠΈΠ³Π»ΠΈΡ†Π΅Ρ€ΠΈΠ΄ΠΎΠ² ΠΈ ΠΎΠ±Ρ‰Π΅Π³ΠΎ холСстСрина ΠΏΡ€ΠΈ достовСрном ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΠΈ холСстСрина Π›ΠŸΠžΠΠŸ ΠΈ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΠΈ Π°Π½Ρ‚ΠΈΠ°Ρ‚Π΅Ρ€ΠΎΠ³Π΅Π½Π½ΠΎΠ³ΠΎ холСстСрина Π›ΠŸΠ’ΠŸ. Β¦

6. ΠŸΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ИАПЀ Π² ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠΉ Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… с ΡΠΎΡ‡Π΅Ρ‚Π°Π½ΠΈΠ΅ΠΌ Π₯БН ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° оказалось высоко эффСктивным ΠΈ ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΠ»ΠΎ ΠΎΠ΄Π½ΠΎΠ²Ρ€Π΅ΠΌΠ΅Π½Π½ΠΎ ΡƒΠΌΠ΅Π½ΡŒΡˆΠΈΡ‚ΡŒ Ρ‚ΠΈΠΏΠΈΡ‡Π½Ρ‹Π΅ проявлСния Π₯БН, Π° Ρ‚Π°ΠΊΠΆΠ΅ ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° Π² Π²ΠΈΠ΄Π΅ Π½ΠΎΡ€ΠΌΠ°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ уровня Π³Π»ΠΈΠΊΠ΅ΠΌΠΈΠΈ, сниТСния Π³Π»ΡŽΠΊΠΎΠ·ΡƒΡ€ΠΈΠΈ, Π°Π»ΡŒΠ±ΡƒΠΌΠΈΠ½ΡƒΡ€ΠΈΠΈ ΠΈ ΠΈΠ½Π΄Π΅ΠΊΡΠ° массы Ρ‚Π΅Π»Π°, ΠΈ ΠΠ“ с Π½ΠΎΡ€ΠΌΠ°Π»ΠΈΠ·Π°Ρ†ΠΈΠ΅ΠΉ Ρ†ΠΈΡ„Ρ€ ΠΠ”.

7. ΠŸΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ БАБ Π² ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠΉ Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… с ΡΠΎΡ‡Π΅Ρ‚Π°Π½ΠΈΠ΅ΠΌ Π₯БН ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° оказалось Π°Π±ΡΠΎΠ»ΡŽΡ‚Π½ΠΎ бСзопасным: Ρ‚Π°ΠΊΠΆΠ΅ ΠΊΠ°ΠΊ ΠΏΡ€ΠΈ Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ ИАПЀ сниТался ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ Π³Π»ΠΈΠΊΠ΅ΠΌΠΈΠΈ (Π½Π° 15,3%), ΠΈ Π°Π»ΡŒΠ±ΡƒΠΌΠΈΠ½ΡƒΡ€ΠΈΠΈ (с 67,8 Π΄ΠΎ 27,3%) ΠΈ Π½ΠΎΡ€ΠΌΠ°Π»ΠΈΠ·ΠΎΠ²Π°Π»ΡΡ Π»ΠΈΠΏΠΈΠ΄Π½Ρ‹ΠΉ спСктр Π² Π²ΠΈΠ΄Π΅ достовСрного сниТСния уровня ΠΎΠ±Ρ‰Π΅Π³ΠΎ (с 6,4 Π΄ΠΎ 5,9 ммоль/Π») ΠΈ Ρ…олСстСрина Π›ΠŸΠžΠΠŸ (Π½Π° 11%) ΠΈ Ρ‚Ρ€ΠΈΠ³Π»ΠΈΡ†Π΅Ρ€ΠΈΠ΄ΠΎΠ² (Π½Π° 13,6%), ΠΏΡ€ΠΈ ΠΎΠ΄Π½ΠΎΠ²Ρ€Π΅ΠΌΠ΅Π½Π½ΠΎΠΌ ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΠΈ холСстСрина Π›ΠŸΠ’ΠŸ (Π½Π° 9,7%). Π’ΠΎ Π΅ΡΡ‚ΡŒ Ρ€Π΅Π°Π»ΡŒΠ½Ρ‹Ρ… прСпятствий ΠΊ Π½Π°Π·Π½Π°Ρ‡Π΅Π½ΠΈΡŽ БАБ Π² ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠΌ Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ Π₯БН, ΡΠΎΡ‡Π΅Ρ‚Π°ΡŽΡ‰Π΅ΠΉΡΡ с Π‘Π” 2 Ρ‚ΠΈΠΏΠ° Π½Π΅ ΠΈΠΌΠ΅Π΅Ρ‚ся.

8. ИспользованиС Π² ΠΊΠΎΠΌΠ±ΠΈΠ½Π°Ρ†ΠΈΠΈ ИАПЀ с Π‘АБ для лСчСния Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… с ΡΠΎΡ‡Π΅Ρ‚Π°Π½ΠΈΠ΅ΠΌ Π₯БН ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° Π½Π΅ ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΠ»ΠΎ Π΄ΠΎΠ±ΠΈΡ‚ΡŒΡΡ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… прСимущСств Π² ΡƒΠ»ΡƒΡ‡ΡˆΠ΅Π½ΠΈΠΈ клиничСских ΠΈ Π»Π°Π±ΠΎΡ€Π°Ρ‚ΠΎΡ€Π½Ρ‹Ρ… ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»Π΅ΠΉ, Π΄Π°ΠΆΠ΅ сниТСниС Π§Π‘Π‘ ΠΈ ΠΠ”, ΡΠ²Π»ΡΡŽΡ‰ΠΈΡ…ΡΡ «Π·Π΅Ρ€ΠΊΠ°Π»ΠΎΠΌ» ΡƒΡΠΏΠ΅ΡˆΠ½ΠΎΠ³ΠΎ примСнСния БАБ Π±Ρ‹Π»ΠΎ ΠΎΠ΄ΠΈΠ½Π°ΠΊΠΎΠ²Ρ‹ΠΌ Π² ΠΏΠΎΠ΄Π³Ρ€ΡƒΠΏΠΏΠ°Ρ… Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… с Π½Π°Π·Π½Π°Ρ‡Π΅Π½ΠΈΠ΅ΠΌ Ρ‚ΠΎΠ»ΡŒΠΊΠΎ ИАПЀ ΠΈ ΠΊΠΎΠΌΠ±ΠΈΠ½Π°Ρ†ΠΈΠΈ ИАПЀ с Π‘АБ.

9. ИзмСнСния Ρ†Π΅Π½Ρ‚Ρ€Π°Π»ΡŒΠ½ΠΎΠΉ Π³Π΅ΠΌΠΎΠ΄ΠΈΠ½Π°ΠΌΠΈΠΊΠΈ Π±Ρ‹Π»ΠΈ ΠΎΡ‚ΠΌΠ΅Ρ‡Π΅Π½Ρ‹ Π² ΠΎΠ±Π΅ΠΈΡ… Π³Ρ€ΡƒΠΏΠΏΠ°Ρ… лСчСния ΠΈ ΠΏΡ€ΠΈ ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠΈ ИАПЀ ΠΈ ΠΈΡ… ΠΊΠΎΠΌΠ±ΠΈΠ½Π°Ρ†ΠΈΠΈ с Π‘АБ, ΠΏΡ€ΠΈΡ‡Π΅ΠΌ Π² Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠ΅ систоличСской Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ Ρ€Π°Π·Π»ΠΈΡ‡ΠΈΠΉ Π½Π΅ Π±Ρ‹Π»ΠΎ выявлСно, ΠΈ Π»ΠΈΡˆΡŒ нормализация диастоличСской Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ Π»Π΅Π²ΠΎΠ³ΠΎ ΠΆΠ΅Π»ΡƒΠ΄ΠΎΡ‡ΠΊΠ° Π΄ΠΎΡΡ‚ΠΈΠ³Π°Π»Π°ΡΡŒ Ρ‚ΠΎΠ»ΡŒΠΊΠΎ ΠΏΡ€ΠΈ сочСтанном ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠΈ ИАПЀ ΠΈ Π‘АБ, Ρ‚. Π΅ ΡΠΎΠ²ΠΌΠ΅ΡΡ‚Π½ΠΎΠ΅ ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ Π΄Π²ΡƒΡ… Π½Π΅ΠΉΡ€ΠΎΠ³ΡƒΠΌΠΎΡ€Π°Π»ΡŒΠ½Ρ‹Ρ… модуляторов ΠΈΠΌΠ΅Π΅Ρ‚ больший ΠΏΠΎΡ‚Π΅Π½Ρ†ΠΈΠ°Π» Π² Π±Π»ΠΎΠΊΠ°Π΄Π΅ процСссов рСмодСлирования ΠΈ Π·Π°ΠΌΠ΅Π΄Π»Π΅Π½ΠΈΠΈ прогрСссирования Π±ΠΎΠ»Π΅Π·Π½ΠΈ.

10.По Π΄Π°Π½Π½Ρ‹ΠΌ рСтроспСктивного Π°Π½Π°Π»ΠΈΠ·Π° имСлась тСндСнция ΠΊ ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΡŽ риска смСрти Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… с Π₯БН ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° Π² ΡΡ€Π°Π²Π½Π΅Π½ΠΈΠΈ с Π±ΠΎΠ»ΡŒΠ½Ρ‹ΠΌΠΈ с Π₯БН (Π½Π° 22%), ΠΏΡ€ΠΈ этом Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° достовСрно ΡƒΡ…ΡƒΠ΄ΡˆΠ°Π΅Ρ‚ ΠΏΡ€ΠΎΠ³Π½ΠΎΠ· Ρƒ ΠΆΠ΅Π½Ρ‰ΠΈΠ½ (Π½Π° 45%), Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с ΠΎΡ‚Π½ΠΎΡΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎ сохранной Π€Π’ Π›Π– (Π½Π° 46%) ΠΈ ΠΏΡ€ΠΈ сохранном БАД (Π½Π° 42%). ΠŸΡ€ΠΈ Π½ΠΈΠ·ΠΊΠΎΠΉ Π€Π’ ΠΈ Π³ΠΈΠΏΠΎΡ‚ΠΎΠ½ΠΈΠΈ Ρ‚ΡΠΆΠ΅ΡΡ‚ΡŒ ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·Π° опрСдСляСтся самой Π₯БН, Π° Π½Π΅ ΠΏΡ€ΠΈΡΠΎΠ΅Π΄ΠΈΠ½ΠΈΠ²ΡˆΠΈΠΌΡΡ Π‘Π” 2 Ρ‚ΠΈΠΏΠ°.

11 .ΠŸΡ€ΠΈ проспСктивном исслСдовании частота сСрдСчно — сосудистых ослоТнСний (ОИМ + ΠΈΠ½ΡΡƒΠ»ΡŒΡ‚Ρ‹ + обострСниС Π₯БН + новая МАУ + стСнокардия) Π² Π³Ρ€ΡƒΠΏΠΏΠ΅ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… с ΡΠΎΡ‡Π΅Ρ‚Π°Π½ΠΈΠ΅ΠΌ Π₯БН ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° Π±Ρ‹Π»Π° достовСрно Π²Ρ‹ΡˆΠ΅, Ρ‡Π΅ΠΌ ΠΏΡ€ΠΈ «ΠΈΠ·ΠΎΠ»ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠΉ» Π₯БН (ΠΏΡ€ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° Π΄Π»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΡŒΡŽ Π±ΠΎΠ»Π΅Π΅ 10 Π»Π΅Ρ‚ — 63,5% ΠΏΡ€ΠΎΡ‚ΠΈΠ² 37,9%). ΠŸΡ€ΠΈ ΠΎΠ΄Π½ΠΎΡ„Π°ΠΊΡ‚ΠΎΡ€Π½ΠΎΠΌ Π°Π½Π°Π»ΠΈΠ·Π΅, Ρ„Π°ΠΊΡ‚ΠΎΡ€Π°ΠΌΠΈ, достовСрно ΠΎΠΏΡ€Π΅Π΄Π΅Π»ΡΡŽΡ‰ΠΈΠΌΠΈ Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠ΅ сСрдСчнососудистых ослоТнСний являлись: возраст, Π΄Π»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ Π΄ΠΈΠ°Π±Π΅Ρ‚Π°, Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ ΠΠ“ Π² Π°Π½Π°ΠΌΠ½Π΅Π·Π΅, больший индСкс массы Ρ‚Π΅Π»Π°, ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΠ΅ Ρ‚Ρ€ΠΈΠ³Π»ΠΈΡ†Π΅Ρ€ΠΈΠ΄ΠΎΠ², диастоличСская дисфункция, Π° Ρ‚Π°ΠΊΠΆΠ΅ Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ ΠΌΠΈΠΊΡ€ΠΎΠ°Π»ΡŒΠ±ΡƒΠΌΠΈΠ½ΡƒΡ€ΠΈΠΈ.

12.Π›Π΅Ρ‡Π΅Π½ΠΈΠ΅ ΠΈΠ½Π³ΠΈΠ±ΠΈΡ‚ΠΎΡ€Π°ΠΌΠΈ АПЀ ΠΈΠ·ΠΎΠ»ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎ ΠΈΠ»ΠΈ Π² ΡΠΎΡ‡Π΅Ρ‚Π°Π½ΠΈΠΈ с |3-Π±Π»ΠΎΠΊΠ°Ρ‚ΠΎΡ€Π°ΠΌΠΈ Π½Π΅ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ‚ достовСрно ΡΠ½ΠΈΠ·ΠΈΡ‚ΡŒ число сСрдСчно — сосудистых ослоТнСний ΠΈ ΡƒΡ€ΠΎΠ²Π½ΡΡ‚ΡŒ риск Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… с ΡΠΎΡ‡Π΅Ρ‚Π°Π½ΠΈΠ΅ΠΌ Π₯БН + Π‘Π” 2 Ρ‚ΠΈΠΏΠ° с ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π°ΠΌΠΈ с ΠΈΠ·ΠΎΠ»ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠΉ Π₯БН. ΠŸΡ€ΠΈ комплСксной Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ ΠΈΠ½Π³ΠΈΠ±ΠΈΡ‚ΠΎΡ€Π°ΠΌΠΈ АПЀ ΠΈ Ρ€-Π±Π»ΠΎΠΊΠ°Ρ‚ΠΎΡ€Π°ΠΌΠΈ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… с Π₯БН ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° имССтся тСндСнция ΠΊ ΠΌΠ΅Π½ΡŒΡˆΠ΅ΠΌΡƒ возникновСнию сСрдСчно — сосудистых ослоТнСний, ΠΏΡ€Π΅ΠΆΠ΄Π΅ всСго, случаСв обострСния Π₯БН. Π’ΠΈΠ΄ΠΈΠΌΠΎ для достовСрного сниТСния риска Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎ агрСссивноС Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅ Π½Π΅ Ρ‚ΠΎΠ»ΡŒΠΊΠΎ Π₯БН, Π½ΠΎ ΠΈ Π²Ρ‚ΠΎΡ€ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½Ρ‚Π°Π‘Π” 2 Ρ‚ΠΈΠΏΠ°.

ΠŸΠ ΠΠšΠ’Π˜Π§Π•Π‘ΠšΠ˜Π• Π Π•ΠšΠžΠœΠ•ΠΠ”ΠΠ¦Π˜Π˜.

1. Учитывая, Ρ‡Ρ‚ΠΎ присоСдинСниС Π‘Π” 2 Ρ‚ΠΈΠΏΠ° ΡΠ΅Ρ€ΡŒΠ΅Π·Π½ΠΎ ослоТняСт Ρ‚Π΅Ρ‡Π΅Π½ΠΈΠ΅ Π₯БН ΠΈ Ρ‚Ρ€Π΅Π±ΡƒΠ΅Ρ‚ ΡΠΏΠ΅Ρ†ΠΈΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ воздСйствия, Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎ Ρ€Π΅ΠΊΠΎΠΌΠ΅Π½Π΄ΠΎΠ²Π°Ρ‚ΡŒ всСм ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π°ΠΌ с Π΄Π΅ΠΊΠΎΠΌΠΏΠ΅Π½ΡΠ°Ρ†ΠΈΠ΅ΠΉ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅ исслСдований, Π½Π°ΠΏΡ€Π°Π²Π»Π΅Π½Π½Ρ‹Ρ… Π½Π° ΡΠ²ΠΎΠ΅Π²Ρ€Π΅ΠΌΠ΅Π½Π½ΠΎΠ΅ выявлСниС Π‘Π” 2 Ρ‚ΠΈΠΏΠ° (ΠΊΠΎΠ½Ρ‚Ρ€ΠΎΠ»ΡŒ Π·Π° ΡƒΡ€ΠΎΠ²Π½Π΅ΠΌ Π³Π»ΡŽΠΊΠΎΠ·Ρ‹ Π½Π°Ρ‚ΠΎΡ‰Π°ΠΊ, ΠΏΡ€ΠΎΠ±Ρ‹ Π½Π° Ρ‚ΠΎΠ»Π΅Ρ€Π°Π½Ρ‚Π½ΠΎΡΡ‚ΡŒ ΠΊ Π³Π»ΡŽΠΊΠΎΠ·Π΅, ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ Π³Π»ΡŽΠΊΠΎΠ·ΡƒΡ€ΠΈΠΈ).

2. Для Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… с ΡΠΎΡ‡Π΅Ρ‚Π°Π½ΠΈΠ΅ΠΌ Π₯БН ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΡ‹ΠΌ являСтся Ρ‚Ρ‰Π°Ρ‚Π΅Π»ΡŒΠ½Ρ‹ΠΉ ΠΊΠΎΠ½Ρ‚Ρ€ΠΎΠ»ΡŒ Π·Π° Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠ΅ΠΉ ΠΏΠΎΡ‡Π΅ΠΊ (ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ уровня ΠΊΡ€Π΅Π°Ρ‚ΠΈΠ½ΠΈ-Π½Π° ΠΈ ΠΌΠΈΠΊΡ€ΠΎΠ°Π»ΡŒΠ±ΡƒΠΌΠΈΠ½ΡƒΡ€ΠΈΠΈ, Π³Π»ΡŽΠΊΠΎΠ·ΡƒΡ€ΠΈΠΈ), Ρ‡Ρ‚ΠΎ ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΡ‚ своСврСмСнно ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΡ‚ΡŒ ΠΊΠΎΡ€Ρ€Π΅ΠΊΡ†ΠΈΡŽ этих Π½Π°Ρ€ΡƒΡˆΠ΅Π½ΠΈΠΉ.

3. НСсмотря Π½Π° Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ Π²Ρ‹Ρ€Π°ΠΆΠ΅Π½Π½ΠΎΠΉ дСкомпСнсации ΠΈ ΡƒΡ…ΡƒΠ΄ΡˆΠ΅Π½ΠΈΠ΅ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ ΠΏΠ΅Ρ‡Π΅Π½ΠΈ, Π±ΠΎΠ»ΡŒΠ½Ρ‹ΠΌ с ΡΠΎΡ‡Π΅Ρ‚Π°Π½ΠΈΠ΅ΠΌ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° ΠΈ Π₯БН Π΄ΠΎΠ»ΠΆΠ½ΠΎ ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΡ‚ΡŒΡΡ рСгулярноС исслСдованиС Π»ΠΈΠΏΠΈΠ΄Π½ΠΎΠ³ΠΎ профиля, Ρ‡Ρ‚ΠΎ ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΡ‚ своСврСмСнно ΠΏΡ€ΠΈΡΠΎΠ΅Π΄ΠΈΠ½ΡΡ‚ΡŒ Π³ΠΈΠΏΠΎΠ»ΠΈΠΏΠΈΠ΄Π΅ΠΌΠΈΡ‡Π΅ΡΠΊΡƒΡŽ Ρ‚Π΅Ρ€Π°ΠΏΠΈΡŽ.

4. МаксимальноС Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ Π΄ΠΎΠ»ΠΆΠ½ΠΎ ΡƒΠ΄Π΅Π»ΡΡ‚ΡŒΡΡ ΠΆΠ΅Π½Ρ‰ΠΈΠ½Π°ΠΌ ΠΈ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π°ΠΌ с ΡΠΎΡ…Ρ€Π°Π½Π½ΠΎΠΉ ΡΠΎΠΊΡ€Π°Ρ‚ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠΉ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠ΅ΠΉ Π›Π– (Π€Π’ > 38%) ΠΈ ΡΠΎΡ…Ρ€Π°Π½Π΅Π½Π½Ρ‹ΠΌ ΡƒΡ€ΠΎΠ²Π½Π΅ΠΌ систоличСского ΠΠ” (> 120 ΠΌΠΌ.Ρ€Ρ‚.ст), Ρ‚.ΠΊ. Ρƒ ΡΡ‚ΠΈΡ… ΠΊΠ°Ρ‚Π΅Π³ΠΎΡ€ΠΈΠΉ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… ΠΈΠΌΠ΅Π½Π½ΠΎ Ρ‚Π΅Ρ‡Π΅Π½ΠΈΠ΅ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° максимально опрСдСляСт число ослоТнСний ΠΈ ΠΏΡ€ΠΎΠ³Π½ΠΎΠ· заболСвания. Π­Ρ‚ΠΈ Π³Ρ€ΡƒΠΏΠΏΡ‹ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… Ρ‚Ρ€Π΅Π±ΡƒΡŽΡ‚ совмСстного контроля ΠΊΠ°Ρ€Π΄ΠΈΠΎΠ»ΠΎΠ³ΠΎΠ² ΠΈ ΡΠ½Π΄ΠΎΠΊΡ€ΠΈΠ½ΠΎΠ»ΠΎΠ³ΠΎΠ².

5. Π›Π΅Ρ‡Π΅Π½ΠΈΠ΅ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… с ΡΠΎΡ‡Π΅Ρ‚Π°Π½ΠΈΠ΅ΠΌ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° ΠΈ Π₯БН Π΄ΠΎΠ»ΠΆΠ½ΠΎ Π²ΠΊΠ»ΡŽΡ‡Π°Ρ‚ΡŒ ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ИАПЀ, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Π΅ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡŽΡ‚ ΡƒΠΌΠ΅Π½ΡŒΡˆΠΈΡ‚ΡŒ Π²Ρ‹Ρ€Π°ΠΆΠ΅Π½Π½ΠΎΡΡ‚ΡŒ дСкомпСнсации, ΠΎΠ΄Π½ΠΎΠ²Ρ€Π΅ΠΌΠ΅Π½Π½ΠΎ Π½ΠΎΡ€ΠΌΠ°Π»ΠΈΠ·ΠΎΠ²Π°Ρ‚ΡŒ АД, Π·Π°Ρ‰ΠΈΡ‚ΠΈΡ‚ΡŒ ΠΏΠΎΡ‡ΠΊΠΈ ΠΈ ΡƒΠ»ΡƒΡ‡ΡˆΠΈΡ‚ΡŒ Ρ‚Π΅Ρ‡Π΅Π½ΠΈΠ΅ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° ΠΈ ΠΎΠ±Π»Π΅Π³Ρ‡ΠΈΡ‚ΡŒ ΠΊΠΎΠ½Ρ‚Ρ€ΠΎΠ»ΡŒ Π·Π° ΡƒΡ€ΠΎΠ²Π½Π΅ΠΌ Π³Π»ΠΈΠΊΠ΅ΠΌΠΈΠΈ.

6. ΠŸΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ БАБ Ρƒ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… с Π₯БН ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° оказалось «ΠΊΡ€Π°ΠΉΠ½Π΅ эффСктивным ΠΈ Π°Π±ΡΠΎΠ»ΡŽΡ‚Π½ΠΎ бСзопасным, Π½Π΅ ΡƒΡΡƒΠ³ΡƒΠ±Π»ΡΡŽΡ‰ΠΈΠΌ тСчСния Π‘Π” 2 Ρ‚ΠΈΠΏΠ°.

7. Π‘ΠΎΡ‡Π΅Ρ‚Π°Π½Π½ΠΎΠ΅ ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ИАПЀ ΠΈ Π‘АБ позволяСт максимально ΡΠ½ΠΈΠΆΠ°Ρ‚ΡŒ риск ослоТнСний, ΡƒΠ»ΡƒΡ‡ΡˆΠ°Ρ‚ΡŒ Ρ‚Π΅Ρ‡Π΅Π½ΠΈΠ΅ Π₯БН ΠΈ ΠΌΠ°ΠΊΡΠΈΠΌΠ°Π»ΡŒΠ½ΠΎ Π±Π»ΠΎΠΊΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ процСссы рСмодСлирования Π›Π–, Ρ‡Ρ‚ΠΎ Π΄Π΅Π»Π°Π΅Ρ‚ Ρ‚Π°ΠΊΠΎΠΉ Ρ€Π΅ΠΆΠΈΠΌ Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ ΠΏΠΎΠΊΠ°Π·Π°Π½Π½Ρ‹ΠΌ всСм Π±ΠΎΠ»ΡŒΠ½Ρ‹ΠΌ с ΡΠΎΡ‡Π΅Ρ‚Π°Π½ΠΈΠ΅ΠΌ Π₯БН ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ°, Π½Π΅ ΠΈΠΌΠ΅ΡŽΡ‰ΠΈΠΌ ΡΠΏΠ΅Ρ†ΠΈΠ°Π»ΡŒΠ½Ρ‹Ρ… ΠΈΠ½Π΄ΠΈΠ²ΠΈΠ΄ΡƒΠ°Π»ΡŒΠ½Ρ‹Ρ… ΠΏΡ€ΠΎΡ‚ΠΈΠ²ΠΎΠΏΠΎΠΊΠ°Π·Π°Π½ΠΈΠΉ.

8. Учитывая, Ρ‡Ρ‚ΠΎ Π΄Π°ΠΆΠ΅ ΠΏΡ€ΠΈ комплСксной Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ ИАПЀ с Π‘АБ риск сСрдСчно — сосудистых ослоТнСний Ρƒ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… с Π₯БН ΠΈ Π‘Π” 2 Ρ‚ΠΈΠΏΠ° остаСтся достовСрно ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½Π½Ρ‹ΠΌ, Π²Π°ΠΆΠ½Ρ‹ΠΌ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½Ρ‚ΠΎΠΌ Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡŽΡ‰Π΅ΠΉ Π΄ΠΎΠ±ΠΈΠ²Π°Ρ‚ΡŒΡΡ сниТСния риска сСрдСчно-сосудистых ослоТнСний Π΄ΠΎΠ»ΠΆΠ½Π° Π±Ρ‹Ρ‚ΡŒ агрСссивная гипогликСмичСская тСрапия.

ΠŸΠΎΠΊΠ°Π·Π°Ρ‚ΡŒ вСсь тСкст

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