Π Π΅Π°Π»ΠΈΠ·Π°ΡΠΈΡ Π°Π»Π³ΠΎΡΠΈΡΠΌΠΎΠ² ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΊΠ²Π°Π½ΡΠΎΠ²ΠΎΠΉ ΠΈ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎΠΉ ΠΌΠ΅Ρ Π°Π½ΠΈΠΊΠΈ ΠΈ ΠΏΡΠΈΠ»ΠΎΠΆΠ΅Π½ΠΈΡ ΠΊ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡΠΌ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΠΎΠ² ΡΠ΅Π°ΠΊΡΠΈΠΉ Π² ΡΠ°ΡΡΠ²ΠΎΡΠ°Ρ ΠΈ Π±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ ΡΠΈΡΡΠ΅ΠΌΠ°Ρ
![ΠΠΈΡΡΠ΅ΡΡΠ°ΡΠΈΡ: Π Π΅Π°Π»ΠΈΠ·Π°ΡΠΈΡ Π°Π»Π³ΠΎΡΠΈΡΠΌΠΎΠ² ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΊΠ²Π°Π½ΡΠΎΠ²ΠΎΠΉ ΠΈ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎΠΉ ΠΌΠ΅Ρ
Π°Π½ΠΈΠΊΠΈ ΠΈ ΠΏΡΠΈΠ»ΠΎΠΆΠ΅Π½ΠΈΡ ΠΊ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡΠΌ ΠΌΠ΅Ρ
Π°Π½ΠΈΠ·ΠΌΠΎΠ² ΡΠ΅Π°ΠΊΡΠΈΠΉ Π² ΡΠ°ΡΡΠ²ΠΎΡΠ°Ρ
ΠΈ Π±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠΈΡΡΠ΅ΠΌΠ°Ρ](https://niscu.ru/work/5139378/cover.png)
ΠΠ°ΠΆΠ΄Π°Ρ ΠΈΠ· ΡΠ°ΡΡΠΌΠΎΡΡΠ΅Π½Π½ΡΡ ΡΠΈΡΡΠ΅ΠΌ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΠ΅Ρ ΠΈΠ½ΡΠ΅ΡΠ΅Ρ Π΄Π»Ρ ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΡΡΡΠ΅ΠΉ ΠΎΠ±Π»Π°ΡΡΠΈ Π±ΠΈΠΎΡΠΈΠ·ΠΈΠΊΠΈ (Π±ΠΈΠΎΡ ΠΈΠΌΠΈΠΈ), Π½ΠΎ Π΄Π»Ρ ΡΠ΅Π»Π΅ΠΉ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΡ ΡΠ°ΠΊΠΆΠ΅ Π²Π°ΠΆΠ½ΠΎ Π±ΡΠ»ΠΎ ΡΡΡΠ°Π½ΠΎΠ²ΠΈΡΡ, Π½Π°ΡΠΊΠΎΠ»ΡΠΊΠΎ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΠΈ ΠΌΠ΅ΡΠΎΠ΄Π° ΠΠ/ΠΠ. Π‘ ΡΡΠΎΠΉ ΡΠ΅Π»ΡΡ Π² ΡΡΠ΄Π΅ ΠΏΡΠΈΠΌΠ΅ΡΠΎΠ² ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΎΡΡ ΡΡΠ°Π²Π½Π΅Π½ΠΈΠ΅ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ² ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ Π²Π°ΡΠΈΠ°Π½ΡΠΎΠ² ΠΠ/ΠΠ. ΠΠΎ Π²ΡΠ΅Ρ ΡΠ»ΡΡΠ°ΡΡ ΡΠ°ΡΡΠ΅ΡΡ Π²ΡΠΏΠΎΠ»Π½ΡΠ»ΠΈΡΡ Π½Π° ΡΡΠΏΠ΅ΡΠΊΠΎΠΌΠΏΡΡΡΠ΅ΡΠ½ΡΡ ΡΠ΅ΡΡΡΡΠ°Ρ ΠΠΠ£ ΠΈΠΌ. Π. Π… Π§ΠΈΡΠ°ΡΡ Π΅ΡΡ >
- Π‘ΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅
- ΠΡΠ΄Π΅ΡΠΆΠΊΠ°
- ΠΠΈΡΠ΅ΡΠ°ΡΡΡΠ°
- ΠΡΡΠ³ΠΈΠ΅ ΡΠ°Π±ΠΎΡΡ
- ΠΠΎΠΌΠΎΡΡ Π² Π½Π°ΠΏΠΈΡΠ°Π½ΠΈΠΈ
Π‘ΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅
- ΠΠ»Π°Π²Π° 1. ΠΠΈΡΠ΅ΡΠ°ΡΡΡΠ½ΡΠΉ ΠΎΠ±Π·ΠΎΡ. ΠΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΡΠ΅ ΠΌΠ΅ΡΠΎΠ΄Ρ ΠΊΠ²Π°Π½ΡΠΎΠ²ΠΎΠΉ ΠΈ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎΠΉ ΠΌΠ΅Ρ
Π°Π½ΠΈΠΊΠΈ
- 1. 1. ΠΠ±ΡΠΈΠ΅ ΡΠ²Π΅Π΄Π΅Π½ΠΈΡ
- 1. 2. ΠΠ΅ΡΠΎΠ΄ ΠΠ/ΠΠ
- 1. 2. 1. Π’Π΅ΡΠΌΠΈΠ½ΠΎΠ»ΠΎΠ³ΠΈΡ
- 1. 2. 2. ΠΠΎΠ»Π½Π°Ρ ΡΠ½Π΅ΡΠ³ΠΈΡ Π² ΠΌΠ΅ΡΠΎΠ΄Π΅ ΠΠ/ΠΠ
- 1. 2. 3. ΠΠ΅Ρ Π°Π½ΠΈΡΠ΅ΡΠΊΠΎΠ΅ Π²Π½Π΅Π΄ΡΠ΅Π½ΠΈΠ΅
- 1. 2. 3. ΠΠ»Π΅ΠΊΡΡΠΎΡΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ Π²Π½Π΅Π΄ΡΠ΅Π½ΠΈΠ΅
- 1. 2. 4. ΠΠΎΠ»ΡΡΠΈΠ·Π°ΡΠΈΠΎΠ½Π½ΠΎΠ΅ Π²Π½Π΅Π΄ΡΠ΅Π½ΠΈΠ΅
- 1. 3. ΠΡΡΠ³ΠΈΠ΅ Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΡ, ΠΈΡΠΏΠΎΠ»ΡΠ·ΡΠ΅ΠΌΡΠ΅ Π² ΠΠ/ΠΠ ΡΡ
Π΅ΠΌΠ°Ρ
- 1. 3. 1. ΠΠ°Π»ΡΠ½ΠΎΠ΄Π΅ΠΉΡΡΠ²ΡΡΡΠΈΠ΅ ΡΠ»Π΅ΠΊΡΡΠΎΡΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΡ
- 1. 3. 2. ΠΠ°Π½-Π΄Π΅Ρ-Π²Π°Π°Π»ΡΡΠΎΠ²ΡΠ΅ Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΡ Π² ΠΌΠ΅ΡΠΎΠ΄Π΅ ΠΠ/ΠΠ
- 1. 3. 3. Π‘Π²ΡΠ·Π°Π½Π½ΡΠ΅ ΠΠ/ΠΠ Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΡ
- 1. 4. Π Π°Π·ΡΡΠ² ΠΌΠ΅ΠΆΠ΄Ρ ΠΠ ΠΈ ΠΠ ΠΏΠΎΠ΄ΡΠΈΡΡΠ΅ΠΌΠ°ΠΌΠΈ ΠΏΠΎ ΠΊΠΎΠ²Π°Π»Π΅Π½ΡΠ½ΠΎΠΉ ΡΠ²ΡΠ·ΠΈ
- 1. 4. 1. ΠΠ±Π·ΠΎΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ²
- 1. 4. 2. ΠΡΠ±ΠΎΡ ΠΌΠ΅ΡΡΠ° ΡΠ°Π·ΡΡΠ²Π°
- 1. 4. 3. LINK-Π°ΡΠΎΠΌΡ
- 1. 4. 4. Π‘Π²ΡΠ·ΡΠ²Π°ΡΡΠΈΠ΅ Π°ΡΠΎΠΌΡ
- 1. 4. 4. ΠΠ°ΠΌΠΎΡΠΎΠΆΠ΅Π½Π½ΡΠ΅ Π»ΠΎΠΊΠ°Π»ΠΈΠ·ΠΎΠ²Π°Π½Π½ΡΠ΅ ΠΎΡΠ±ΠΈΡΠ°Π»ΠΈ
- 1. 5. ΠΡΠΎΠ³ΡΠ°ΠΌΠΌΠ½ΡΠ΅ ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΠΈ ΠΌΠ΅ΡΠΎΠ΄Π° ΠΠ/ΠΠ
- 1. 6. ΠΠ΅ΡΠΎΠ΄ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»ΠΎΠ² ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ ΡΡΠ°Π³ΠΌΠ΅Π½ΡΠΎΠ²
- ΠΠ»Π°Π²Π° 2. ΠΠ΅ΡΠΎΠ΄ ΠΊΠΎΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎ-ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΡΡ
ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ
ΡΡΠ°Π³ΠΌΠ΅Π½ΡΠΎΠ²
- 2. 1. ΠΠ²Π΅Π΄Π΅Π½ΠΈΠ΅
- 2. 2. ΠΠΎΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎ-ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΡΠ΅ ΠΆΡΡΡΠΊΠΈΠ΅ ΡΡΠ°Π³ΠΌΠ΅Π½ΡΡ
- 2. 3. ΠΠ»Π΅ΠΊΡΡΠΎΡΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΠ΅
- 2. 4. Π Π°Π·ΡΡΠ² ΠΏΠΎ ΠΊΠΎΠ²Π°Π»Π΅Π½ΡΠ½ΠΎΠΉ ΡΠ²ΡΠ·ΠΈ
- 2. 5. Π Π°ΡΡΡΡ ΡΠΈΠ» Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΡ ΠΠ/ΠΠ
- 2. 6. Π Π΅Π°Π»ΠΈΠ·Π°ΡΠΈΡ ΠΌΠ΅ΡΠΎΠ΄Π° ΠΊΠΎΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎ-ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ ΡΡΠ°Π³ΠΌΠ΅Π½ΡΠΎΠ²
- ΠΠ»Π°Π²Π° 3. ΠΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ΅Π°ΠΊΡΠΈΠΈ Π³ΠΈΠ΄ΡΠΎΠ»ΠΈΠ·Π° ΡΠΈΠΊΠ»ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π³ΡΠ°Π½ΠΎΠ·ΠΈΠ½ΠΌΠΎΠ½ΠΎΡΠΎΡΡΠ°ΡΠ° Π² Π²ΠΎΠ΄Π½ΠΎΠΌ ΡΠ°ΡΡΠ²ΠΎΡΠ΅
- 3. 1. ΠΠ²Π΅Π΄Π΅Π½ΠΈΠ΅
- 3. 2. Π¦ΠΈΠΊΠ»ΠΈΡΠ΅ΡΠΊΠΈΠΉ Π³ΡΠ°Π½ΠΎΠ·ΠΈΠ½ΠΌΠΎΠ½ΠΎΡΠΎΡΡΠ°Ρ (ΡΠΠΠ€)
- 3. 3. ΠΡΠΎΡΠΎΠΊΠΎΠ» Π²ΡΡΠΈΡΠ»Π΅Π½ΠΈΠΉ
- 3. 4. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ
- 3. 5. ΠΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ²
- ΠΠ»Π°Π²Π° 4. ΠΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ΅Π°ΠΊΡΠΈΠΈ Π³ΠΈΠ΄ΡΠΎΠ»ΠΈΠ·Π° Π°ΡΠ΅ΡΠΈΠ»Ρ
ΠΎΠ»ΠΈΠ½Π° Π² Π°ΠΊΡΠΈΠ²Π½ΠΎΠΌ ΡΠ΅Π½ΡΡΠ΅ ΡΠ΅ΡΠΌΠ΅Π½ΡΠ° Π°ΡΠ΅ΡΠΈΠ»Ρ
ΠΎΠ»ΠΈΠ½ΡΡΡΠ΅ΡΠ°Π·Ρ
- 4. 1. Π€Π΅ΡΠΌΠ΅Π½Ρ Π°ΡΠ΅ΡΠΈΠ»Ρ ΠΎΠ»ΠΈΠ½ΡΡΡΠ΅ΡΠ°Π·Π°
- 4. 2. ΠΠΎΠ΄Π΅Π»ΡΠ½Π°Ρ ΡΠΈΡΡΠ΅ΠΌΠ° ΠΈ ΠΏΡΠΎΡΠΎΠΊΠΎΠ» Π²ΡΡΠΈΡΠ»Π΅Π½ΠΈΠΉ
- 4. 3. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ
- 4. 4. ΠΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ²
- 4. 4. 1. Π ΠΎΠ»Ρ ΠΊΠ²Π°Π½ΡΠΎΠ²ΠΎ-Ρ ΠΈΠΌΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΌΠ΅ΡΠΎΠ΄Π° ΠΈ ΠΠ/ΠΠ ΡΠ°Π·Π΄Π΅Π»Π΅Π½ΠΈΡ ΡΠΈΡΡΠ΅ΠΌΡ
- 4. 4. 2. Π ΠΎΠ»Ρ Π½Π°ΡΠ°Π»ΡΠ½ΠΎΠΉ ΠΊΡΠΈΡΡΠ°Π»Π»ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΡΡΡΠΊΡΡΡΡ
- 4. 4. 3. Π‘ΡΠ°Π²Π½Π΅Π½ΠΈΠ΅ Π΄Π²ΡΡ ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΠ/ΠΠ
- 5. 1. ΠΠ΅Π»ΡΠ½ΡΠΉ ΡΠ»ΡΠΎΡΠ΅ΡΡΠ΅Π½ΡΠ½ΡΠΉ Π±Π΅Π»ΠΎΠΊ (Π²Π Π )
- 5. 2. Π€ΠΎΡΠΎΡΠ΅Π°ΠΊΡΠΈΡ Π΄Π΅ΠΊΠ°ΡΠ±ΠΎΠΊΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π²ΠΠ
- 5. 3. ΠΠΎΠ΄Π΅Π»ΡΠ½Π°Ρ ΡΠΈΡΡΠ΅ΠΌΠ° ΠΈ ΠΏΡΠΎΡΠΎΠΊΠΎΠ» Π²ΡΡΠΈΡΠ»Π΅Π½ΠΈΠΉ
- 5. 4. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ
- 5. 4. 1. ΠΠ»Π΅ΠΊΡΡΠΎΠ½Π½ΡΠΉ ΠΏΠ΅ΡΠ΅Ρ ΠΎΠ΄ 80−81 Π² Π-ΠΠΠ
- 5. 4. 2. ΠΠ»Π΅ΠΊΡΡΠΎΠ½Π½ΡΠ΅ ΠΏΠ΅ΡΠ΅Ρ ΠΎΠ΄Ρ 8ΠΎ-8ΠΏ (ΠΏ>1) Π² Π½Π΅ΠΉΡΡΠ°Π»ΡΠ½ΠΎΠΌ Ρ ΡΠΎΠΌΠΎΡΠΎΡΠ΅ vt-GFPl
- 5. 4. 3. ΠΠΎΠ·Π±ΡΠΆΠ΄Π΅Π½ΠΈΡ Π½Π° ΡΡΠΎΠ²Π½ΠΈ Ρ ΠΏΠ΅ΡΠ΅Π½ΠΎΡΠΎΠΌ ΡΠ»Π΅ΠΊΡΡΠΎΠ½Π° 8Π‘Π’
- 5. 4. 4. ΠΠ»ΠΈΡΠ½ΠΈΠ΅ ΠΌΡΡΠ°ΡΠΈΠΈ ΠΠΈΠΠΠΠΠ²
- 5. 5. ΠΠΎΠ·ΠΌΠΎΠΆΠ½ΡΠ΅ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΡ ΠΏΡΠΎΡΠ΅ΡΡΠ° Π΄Π΅ΠΊΠ°ΡΠ±ΠΎΠΊΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ vt-GFP
Π Π΅Π°Π»ΠΈΠ·Π°ΡΠΈΡ Π°Π»Π³ΠΎΡΠΈΡΠΌΠΎΠ² ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΊΠ²Π°Π½ΡΠΎΠ²ΠΎΠΉ ΠΈ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎΠΉ ΠΌΠ΅Ρ Π°Π½ΠΈΠΊΠΈ ΠΈ ΠΏΡΠΈΠ»ΠΎΠΆΠ΅Π½ΠΈΡ ΠΊ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡΠΌ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΠΎΠ² ΡΠ΅Π°ΠΊΡΠΈΠΉ Π² ΡΠ°ΡΡΠ²ΠΎΡΠ°Ρ ΠΈ Π±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ ΡΠΈΡΡΠ΅ΠΌΠ°Ρ (ΡΠ΅ΡΠ΅ΡΠ°Ρ, ΠΊΡΡΡΠΎΠ²Π°Ρ, Π΄ΠΈΠΏΠ»ΠΎΠΌ, ΠΊΠΎΠ½ΡΡΠΎΠ»ΡΠ½Π°Ρ)
Π‘ΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΠ΅ ΠΌΠ΅ΡΠΎΠ΄Ρ ΠΊΠΎΠΌΠΏΡΡΡΠ΅ΡΠ½ΠΎΠ³ΠΎ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΎΠΊΠ°Π·ΡΠ²Π°ΡΡ ΡΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ ΠΏΠΎΠ΄Π΄Π΅ΡΠΆΠΊΡ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΡΠΌ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡΠΌ ΡΠ»ΠΎΠΆΠ½ΡΡ Π±ΠΈΠΎΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΡΡ ΡΠΈΡΡΠ΅ΠΌ, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡ ΡΠ°ΡΡΡΠΈΡΡΠ²Π°ΡΡ Π³Π΅ΠΎΠΌΠ΅ΡΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΡ Π±ΠΈΠΎΠΌΠΎΠ»Π΅ΠΊΡΠ», ΠΎΡΠ΅Π½ΠΈΠ²Π°ΡΡ ΡΠ½Π΅ΡΠ³ΠΈΠΈ ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ ΠΊΠΎΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΉ, ΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΡ ΠΈ ΠΈΠ½ΡΠ΅Π½ΡΠΈΠ²Π½ΠΎΡΡΠΈ ΡΠΏΠ΅ΠΊΡΡΠ°Π»ΡΠ½ΡΡ ΠΏΠΎΠ»ΠΎΡ. ΠΠ½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΡΡ ΡΠΎΠ»Ρ Π² ΠΏΠΎΠ΄ΠΎΠ±Π½ΠΎΠΌ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ Π·Π°Π½ΠΈΠΌΠ°ΡΡ ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΡΠ΅ ΠΌΠ΅ΡΠΎΠ΄Ρ ΠΊΠ²Π°Π½ΡΠΎΠ²ΠΎΠΉ ΠΈ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎΠΉ ΠΌΠ΅Ρ Π°Π½ΠΈΠΊΠΈ (ΠΠ/ΠΠ), ΡΠΎΡΠ΅ΡΠ°ΡΡΠΈΠ΅ Π² ΡΠ΅Π±Π΅ ΡΠΎΡΠ½ΠΎΡΡΡ ΠΊΠ²Π°Π½ΡΠΎΠ²ΡΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ², Π½Π΅ΠΎΠ±Ρ ΠΎΠ΄ΠΈΠΌΡΡ Π΄Π»Ρ ΠΎΠΏΠΈΡΠ°Π½ΠΈΡ Ρ ΠΈΠΌΠΈΡΠ΅ΡΠΊΠΈΡ ΡΠ΅Π°ΠΊΡΠΈΠΉ Π² ΡΠΈΡΡΠ΅ΠΌΠ΅, ΠΈ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΠΈ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎ-ΠΌΠ΅Ρ Π°Π½ΠΈΡΠ΅ΡΠΊΠΈΡ ΠΏΠΎΠ΄Ρ ΠΎΠ΄ΠΎΠ² ΠΏΡΠΈ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ ΡΠΈΡΡΠ΅ΠΌ, ΡΠΎΡΡΠΎΡΡΠΈΡ ΠΈΠ· Π΄Π΅ΡΡΡΠΊΠΎΠ² ΡΡΡΡΡ Π°ΡΠΎΠΌΠΎΠ². Π Π°Π·ΡΠ°Π±ΠΎΡΠΊΠ° Π½ΠΎΠ²ΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ Π°Π»Π³ΠΎΡΠΈΡΠΌΠΎΠ² ΠΌΠ΅ΡΠΎΠ΄Π° ΠΠ/ΠΠ, ΠΎΡΠΈΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ Π½Π° ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΠ΅ ΡΡΠΏΠ΅ΡΠΊΠΎΠΌΠΏΡΡΡΠ΅ΡΡ, ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΠ΅Ρ Π°ΠΊΡΡΠ°Π»ΡΠ½ΡΡ Π·Π°Π΄Π°ΡΡ Π²ΡΡΠΈΡΠ»ΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΠΈ ΠΊΠ²Π°Π½ΡΠΎΠ²ΠΎΠΉ Ρ ΠΈΠΌΠΈΠΈ.
ΠΡΠ½ΠΎΠ²Π½ΠΎΠ΅ Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ Π² Π΄ΠΈΡΡΠ΅ΡΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΠ΅ ΡΠ΄Π΅Π»Π΅Π½ΠΎ Π½ΠΎΠ²ΠΎΠΉ ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΠΈ ΠΌΠ΅ΡΠΎΠ΄ΠΈΠΊΠΈ ΠΠ/ΠΠ Ρ ΠΊΠΎΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎ-ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΡΠΌΠΈ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΠΌΠΈ ΡΡΠ°Π³ΠΌΠ΅Π½ΡΠ°ΠΌΠΈ ΠΈ Π΅Π΅ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ ΠΊ ΠΊΠΎΠ½ΠΊΡΠ΅ΡΠ½ΡΠΌ Π·Π°Π΄Π°ΡΠ°ΠΌ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Ρ ΠΈΠΌΠΈΡΠ΅ΡΠΊΠΈΡ ΠΏΡΠ΅Π²ΡΠ°ΡΠ΅Π½ΠΈΠΉ, Π²ΠΊΠ»ΡΡΠ°Ρ:
β’ ΡΠ΅Π°ΠΊΡΠΈΠΈ Π² ΡΠ°ΡΡΠ²ΠΎΡΠ°Ρ — ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ΅Π°ΠΊΡΠΈΠΈ Π³ΠΈΠ΄ΡΠΎΠ»ΠΈΠ·Π° ΡΠΈΠΊΠ»ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π³ΡΠ°Π½ΠΎΠ·ΠΈΠ½ΠΌΠΎΠ½ΠΎΡΠΎΡΡΠ°ΡΠ° Π² Π²ΠΎΠ΄Π΅,.
β’ ΡΠ΅ΡΠΌΠ΅Π½ΡΠ°ΡΠΈΠ²Π½ΡΠ΅ ΡΠ΅Π°ΠΊΡΠΈΠΈ — ΡΠ°ΡΡΠ΅ΠΏΠ»Π΅Π½ΠΈΠ΅ Π½Π΅ΠΉΡΠΎΠΌΠ΅Π΄ΠΈΠ°ΡΠΎΡΠ° Π°ΡΠ΅ΡΠΈΠ»Ρ ΠΎΠ»ΠΈΠ½Π° ΡΠ΅ΡΠΌΠ΅Π½ΡΠΎΠΌ Π°ΡΠ΅ΡΠΈΠ»Ρ ΠΎΠ»ΠΈΠ½ΡΡΡΠ΅ΡΠ°Π·ΠΎΠΉ,.
β’ ΡΠΎΡΠΎΡΠ΅Π°ΠΊΡΠΈΠΈ Π² Π±Π΅Π»ΠΊΠ°Ρ — Π΄Π΅ΠΊΠ°ΡΠ±ΠΎΠΊΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ Π·Π΅Π»Π΅Π½ΠΎΠ³ΠΎ ΡΠ»ΡΠΎΡΠ΅ΡΡΠ΅Π½ΡΠ½ΠΎΠ³ΠΎ Π±Π΅Π»ΠΊΠ°.
ΠΠ°ΠΆΠ΄Π°Ρ ΠΈΠ· ΡΠ°ΡΡΠΌΠΎΡΡΠ΅Π½Π½ΡΡ ΡΠΈΡΡΠ΅ΠΌ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΠ΅Ρ ΠΈΠ½ΡΠ΅ΡΠ΅Ρ Π΄Π»Ρ ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΡΡΡΠ΅ΠΉ ΠΎΠ±Π»Π°ΡΡΠΈ Π±ΠΈΠΎΡΠΈΠ·ΠΈΠΊΠΈ (Π±ΠΈΠΎΡ ΠΈΠΌΠΈΠΈ), Π½ΠΎ Π΄Π»Ρ ΡΠ΅Π»Π΅ΠΉ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΡ ΡΠ°ΠΊΠΆΠ΅ Π²Π°ΠΆΠ½ΠΎ Π±ΡΠ»ΠΎ ΡΡΡΠ°Π½ΠΎΠ²ΠΈΡΡ, Π½Π°ΡΠΊΠΎΠ»ΡΠΊΠΎ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΠΈ ΠΌΠ΅ΡΠΎΠ΄Π° ΠΠ/ΠΠ. Π‘ ΡΡΠΎΠΉ ΡΠ΅Π»ΡΡ Π² ΡΡΠ΄Π΅ ΠΏΡΠΈΠΌΠ΅ΡΠΎΠ² ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΎΡΡ ΡΡΠ°Π²Π½Π΅Π½ΠΈΠ΅ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ² ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ Π²Π°ΡΠΈΠ°Π½ΡΠΎΠ² ΠΠ/ΠΠ. ΠΠΎ Π²ΡΠ΅Ρ ΡΠ»ΡΡΠ°ΡΡ ΡΠ°ΡΡΠ΅ΡΡ Π²ΡΠΏΠΎΠ»Π½ΡΠ»ΠΈΡΡ Π½Π° ΡΡΠΏΠ΅ΡΠΊΠΎΠΌΠΏΡΡΡΠ΅ΡΠ½ΡΡ ΡΠ΅ΡΡΡΡΠ°Ρ ΠΠΠ£ ΠΈΠΌ. Π. Π. ΠΠΎΠΌΠΎΠ½ΠΎΡΠΎΠ²Π° ΠΈΠ»ΠΈ Π ΠΎΡΡΠΈΠΉΡΠΊΠΎΠΉ Π°ΠΊΠ°Π΄Π΅ΠΌΠΈΠΈ Π½Π°ΡΠΊ.
Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ: Π Π°Π·Π²ΠΈΡΠΈΠ΅ Π°Π»Π³ΠΎΡΠΈΡΠΌΠΎΠ² ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠΎΠ΄Π° ΠΊΠ²Π°Π½ΡΠΎΠ²ΠΎΠΉ ΠΈ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎΠΉ ΠΌΠ΅Ρ Π°Π½ΠΈΠΊΠΈ (ΠΠ/ΠΠ), ΠΎΡΠΈΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ Π½Π° ΡΡΠΏΠ΅ΡΠΊΠΎΠΌΠΏΡΡΡΠ΅ΡΡ, ΠΈ Π΅Π³ΠΎ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ Π΄Π»Ρ ΠΏΡΠΎΠ³Π½ΠΎΠ·ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΠΎΠ² ΡΠ΅Π°ΠΊΡΠΈΠΉ, ΠΏΡΠΎΡ ΠΎΠ΄ΡΡΠΈΡ Π² Π±Π΅Π»ΠΊΠ°Ρ ΠΈ ΡΠ°ΡΡΠ²ΠΎΡΠ°Ρ . Π ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΠΈΠΈ Ρ ΠΏΠΎΡΡΠ°Π²Π»Π΅Π½Π½ΠΎΠΉ ΡΠ΅Π»ΡΡ ΡΠ΅ΡΠ°Π»ΠΈΡΡ ΡΠ»Π΅Π΄ΡΡΡΠΈΠ΅ Π·Π°Π΄Π°ΡΠΈ:
1. Π Π΅Π°Π»ΠΈΠ·Π°ΡΠΈΡ ΠΌΠ΅ΡΠΎΠ΄Π° ΠΠ/ΠΠ Π² Π²Π°ΡΠΈΠ°Π½ΡΠ΅ ΠΊΠΎΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎ-ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ ΡΡΠ°Π³ΠΌΠ΅Π½ΡΠΎΠ² Π² ΠΏΡΠΎΠ³ΡΠ°ΠΌΠΌΠ½ΠΎΠΌ ΠΏΠ°ΠΊΠ΅ΡΠ΅ GAMESS (US).
2. ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΠ° ΡΠ΅Π°ΠΊΡΠΈΠΈ Π³ΠΈΠ΄ΡΠΎΠ»ΠΈΠ·Π° ΡΠΈΠΊΠ»ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π³ΡΠ°Π½ΠΎΠ·ΠΈΠ½ΠΌΠΎΠ½ΠΎΡΠΎΡΡΠ°ΡΠ° Π² Π²ΠΎΠ΄Π½ΠΎΠΌ ΡΠ°ΡΡΠ²ΠΎΡΠ΅ Π΄Π²ΡΠΌΡ ΡΠ°Π·Π»ΠΈΡΠ½ΡΠΌΠΈ Π²Π°ΡΠΈΠ°Π½ΡΠ°ΠΌΠΈ ΠΌΠ΅ΡΠΎΠ΄Π° ΠΠ/ΠΠ.
3. ΠΠ΅ΡΠ°Π»ΠΈΠ·Π°ΡΠΈΡ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΠ° ΡΠ°ΡΡΠ΅ΠΏΠ»Π΅Π½ΠΈΡ Π°ΡΠ΅ΡΠΈΠ»Ρ ΠΎΠ»ΠΈΠ½Π° Π² Π°ΠΊΡΠΈΠ²Π½ΠΎΠΌ ΡΠ΅Π½ΡΡΠ΅ Π°ΡΠ΅ΡΠΈΠ»Ρ ΠΎΠ»ΠΈΠ½ΡΡΡΠ΅ΡΠ°Π·Ρ Π΄Π²ΡΠΌΡ ΡΠ°Π·Π»ΠΈΡΠ½ΡΠΌΠΈ Π²Π°ΡΠΈΠ°Π½ΡΠ°ΠΌΠΈ ΠΌΠ΅ΡΠΎΠ΄Π° ΠΠ/ΠΠ.
4. ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠΎΡΠΎΡΠ΅Π°ΠΊΡΠΈΠΈ Π΄Π΅ΠΊΠ°ΡΠ±ΠΎΠΊΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π·Π΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ»ΡΠΎΡΠ΅ΡΡΠ΅Π½ΡΠ½ΠΎΠ³ΠΎ Π±Π΅Π»ΠΊΠ°.
ΠΠ°ΡΡΠ½Π°Ρ Π½ΠΎΠ²ΠΈΠ·Π½Π° ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ²:
1. ΠΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ Π½ΠΎΠ²ΡΠΉ Π²Π°ΡΠΈΠ°Π½Ρ ΠΊΠΎΠΌΠΏΡΡΡΠ΅ΡΠ½ΠΎΠΉ ΠΏΡΠΎΠ³ΡΠ°ΠΌΠΌΡ ΠΌΠ΅ΡΠΎΠ΄Π° ΠΠ/ΠΠ Ρ ΠΊΠΎΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎ-ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΡΠΌΠΈ ΡΡΠ°Π³ΠΌΠ΅Π½ΡΠ°ΠΌΠΈ, ΡΠ΅Π°Π»ΠΈΠ·ΠΎΠ²Π°Π½Π½ΡΠΉ Π² ΠΏΠ°ΠΊΠ΅ΡΠ΅ GAMESS (US), Π΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΡΠ΅Ρ Π²ΡΡΠΎΠΊΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΏΡΠΈ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠΈ ΡΠ°ΡΡΡΡΠΎΠ² Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΡΡΠΏΠ΅ΡΠΊΠΎΠΌΠΏΡΡΡΠ΅ΡΠΎΠ².
2. Π£ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ, ΡΡΠΎ ΡΠ΅Π°ΠΊΡΠΈΡ Π³ΠΈΠ΄ΡΠΎΠ»ΠΈΠ·Π° ΡΠΈΠΊΠ»ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π³ΡΠ°Π½ΠΎΠ·ΠΈΠ½ΠΌΠΎΠ½ΠΎΡΠΎΡΡΠ°ΡΠ° Π² Π²ΠΎΠ΄Π½ΠΎΠΌ ΡΠ°ΡΡΠ²ΠΎΡΠ΅ ΠΏΡΠΎΡ ΠΎΠ΄ΠΈΡ ΠΏΠΎ Π°ΡΡΠΎΡΠΈΠ°ΡΠΈΠ²Π½ΠΎΠΌΡ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΡ ΡΠ΅ΡΠ΅Π· ΠΈΠ½ΡΠ΅ΡΠΌΠ΅Π΄ΠΈΠ°Ρ Ρ ΠΏΠ΅Π½ΡΠ°ΠΊΠΎΠΎΡΠ΄ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΡΠΌ ΡΠΎΡΡΠΎΡΠΎΠΌ.
3. ΠΠΎΠ΄ΡΠ²Π΅ΡΠΆΠ΄Π΅Π½Π° Π³ΠΈΠΏΠΎΡΠ΅Π·Π° ΠΎ ΡΡΠ°Π±ΠΈΠ»ΡΠ½ΠΎΡΡΠΈ ΡΠ΅ΡΡΠ°ΡΠ΄ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΈΠ½ΡΠ΅ΡΠΌΠ΅Π΄ΠΈΠ°ΡΠ° ΡΡΠ°Π΄ΠΈΠΈ Π°ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠ΅Π°ΠΊΡΠΈΠΈ Π³ΠΈΡΠΎΠ»ΠΈΠ·Π° Π°ΡΠ΅ΡΠΈΠ»Ρ ΠΎΠ»ΠΈΠ½Π° Π² Π°ΠΊΡΠΈΠ²Π½ΠΎΠΌ ΡΠ΅Π½ΡΡΠ΅ ΡΠ΅ΡΠΌΠ΅Π½ΡΠ° Π°ΡΠ΅ΡΠΈΠ»Ρ ΠΎΠ»ΠΈΠ½ΡΡΡΠ΅ΡΠ°Π·Ρ.
4. ΠΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ ΡΠΊΠΎΡΠΎΡΡΡ ΡΠ΅Π°ΠΊΡΠΈΠΈ Π΄Π΅ΠΊΠ°ΡΠ±ΠΎΠΊΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π·Π΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ»ΡΠΎΡΠ΅ΡΡΠ΅Π½ΡΠ½ΠΎΠ³ΠΎ Π±Π΅Π»ΠΊΠ° Π·Π°Π²ΠΈΡΠΈΡ ΠΎΡ Π΄Π»ΠΈΠ½Ρ Π²ΠΎΠ»Π½Ρ ΠΎΠ±Π»ΡΡΠ°ΡΡΠ΅Π³ΠΎ ΡΠ²Π΅ΡΠ°, ΠΈ ΡΠ΅Π°ΠΊΡΠΈΡ ΠΌΠΎΠΆΠ΅Ρ ΠΏΡΠΎΠΈΡΡ ΠΎΠ΄ΠΈΡΡ ΠΊΠ°ΠΊ ΠΏΠΎ ΠΎΠ΄Π½ΠΎΡΠΎΡΠΎΠ½Π½ΠΎΠΌΡ, ΡΠ°ΠΊ ΠΈ ΠΏΠΎ Π΄Π²ΡΡ ΡΠΎΡΠΎΠ½Π½ΠΎΠΌΡ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΡ.
ΠΠΈΡΠ½ΡΠΉ Π²ΠΊΠ»Π°Π΄ Π΄ΠΈΡΡΠ΅ΡΡΠ°Π½ΡΠ° Π·Π°ΠΊΠ»ΡΡΠ°Π΅ΡΡΡ Π² ΡΠ±ΠΎΡΠ΅ ΠΈ Π°Π½Π°Π»ΠΈΠ·Π΅ Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΠ½ΡΡ Π΄Π°Π½Π½ΡΡ , ΠΏΠΎΡΡΠ°Π½ΠΎΠ²ΠΊΠ΅ Π·Π°Π΄Π°Ρ, ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠ΅ ΠΏΡΡΠ΅ΠΉ ΡΠ΅ΡΠ΅Π½ΠΈΡ ΠΏΠΎΡΡΠ°Π²Π»Π΅Π½Π½ΡΡ Π·Π°Π΄Π°Ρ, ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΡ Π°Π»Π³ΠΎΡΠΈΡΠΌΠΎΠ² ΠΌΠ΅ΡΠΎΠ΄Π° ΠΊΠΎΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎ-ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ ΡΡΠ°Π³ΠΌΠ΅Π½ΡΠΎΠ² Π² ΠΏΡΠΎΠ³ΡΠ°ΠΌΠΌΠ½ΠΎΠΌ ΠΏΠ°ΠΊΠ΅ΡΠ΅ ΠΠΠΠ88(ΠΈ8), ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠΈ Π²ΡΡΠΈΡΠ»Π΅Π½ΠΈΠΉ ΠΌΠ΅ΡΠΎΠ΄Π°ΠΌΠΈ ΠΊΠ²Π°Π½ΡΠΎΠ²ΠΎΠΉ Ρ ΠΈΠΌΠΈΠΈ, ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΡΠΌΠΈ ΠΌΠ΅ΡΠΎΠ΄Π°ΠΌΠΈ ΠΊΠ²Π°Π½ΡΠΎΠ²ΠΎΠΉ ΠΈ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎΠΉ ΠΌΠ΅Ρ Π°Π½ΠΈΠΊΠΈ, ΠΈΠ½ΡΠ΅ΡΠΏΡΠ΅ΡΠ°ΡΠΈΠΈ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ², ΠΏΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΠ΅ ΠΏΡΠ±Π»ΠΈΠΊΠ°ΡΠΈΠΉ ΠΈ Π΄ΠΎΠΊΠ»Π°Π΄ΠΎΠ² ΠΏΠΎ ΡΠ΅ΠΌΠ΅ Π΄ΠΈΡΡΠ΅ΡΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΡ.
ΠΠ°ΡΡΠ½Π°Ρ ΠΈ ΠΏΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠ°Ρ Π·Π½Π°ΡΠΈΠΌΠΎΡΡΡ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΡ Π·Π°ΠΊΠ»ΡΡΠ°Π΅ΡΡΡ Π² ΡΠΎΠΌ, ΡΡΠΎ ΠΏΠΎΠ»ΡΡΠ΅Π½Π½ΡΠ΅ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡ Π΄Π΅ΡΠ°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°ΡΡ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΡ ΡΠ΅ΡΠΌΠ΅Π½ΡΠ°ΡΠΈΠ²Π½ΡΡ ΠΈ ΡΠΎΡΠΎΡ ΠΈΠΌΠΈΡΠ΅ΡΠΊΠΈΡ ΡΠ΅Π°ΠΊΡΠΈΠΉ Π΄Π»Ρ ΡΠΈΡΠΎΠΊΠΎΠ³ΠΎ ΠΊΠ»Π°ΡΡΠ° Π±Π΅Π»ΠΊΠΎΠ². Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΡ ΠΌΠΎΠ³ΡΡ Π±ΡΡΡ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½Ρ, Π² ΡΠ°ΡΡΠ½ΠΎΡΡΠΈ, Π΄Π»Ρ ΠΏΡΠΎΠ³Π½ΠΎΠ·ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠ²ΠΎΠΉΡΡΠ² Π½ΠΎΠ²ΡΡ ΠΏΠ΅ΡΡΠΏΠ΅ΠΊΡΠΈΠ²Π½ΡΡ Π±ΠΈΠΎΠΌΠ°ΡΠΊΠ΅ΡΠΎΠ² Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ ΡΠ»ΡΠΎΡΠ΅ΡΡΠ΅Π½ΡΠ½ΡΡ Π±Π΅Π»ΠΊΠΎΠ², Π½ΠΎΠ²ΡΡ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»ΡΠ½ΡΡ ΠΈΠ½Π³ΠΈΠ±ΠΈΡΠΎΡΠΎΠ² Π²Π°ΠΆΠ½Π΅ΠΉΡΠ΅Π³ΠΎ ΡΠ΅ΡΠΌΠ΅Π½ΡΠ° Π²ΡΡΡΠ΅ΠΉ Π½Π΅ΡΠ²Π½ΠΎΠΉ Π΄Π΅ΡΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ — Π°ΡΠ΅ΡΠΈΠ»Ρ ΠΎΠ»ΠΈΠ½ΡΡΡΠ΅ΡΠ°Π·Ρ.
ΠΠΏΡΠΎΠ±Π°ΡΠΈΡ ΡΠ°Π±ΠΎΡΡ ΠΈ ΠΏΡΠ±Π»ΠΈΠΊΠ°ΡΠΈΠΈ. ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ Π΄ΠΈΡΡΠ΅ΡΡΠ°ΡΠΈΠΈ Π±ΡΠ»ΠΈ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ Π½Π° ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΡΡ ΠΊΠΎΠ½ΡΠ΅ΡΠ΅Π½ΡΠΈΡΡ «ΠΠΎΠΌΠΎΠ½ΠΎΡΠΎΠ²» (ΠΠΎΡΠΊΠ²Π° 2009 ΠΈ 2011), 7-ΠΉ ΠΡΠ΅ΡΠΎΡΡΠΈΠΉΡΠΊΠΎΠΉ ΠΊΠΎΠ½ΡΠ΅ΡΠ΅Π½ΡΠΈΠΈ «ΠΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎΠ΅ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅» (ΠΠΎΡΠΊΠ²Π° 2011), IX ΠΈ X Π΅ΠΆΠ΅Π³ΠΎΠ΄Π½ΡΡ ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΡΡ ΠΌΠΎΠ»ΠΎΠ΄Π΅ΠΆΠ½ΡΡ ΠΊΠΎΠ½ΡΠ΅ΡΠ΅Π½ΡΠΈΡΡ «ΠΠΈΠΎΡ ΠΈΠΌΠΈΡΠ΅ΡΠΊΠ°Ρ ΡΠΈΠ·ΠΈΠΊΠ°» ΠΠΠ₯Π€ Π ΠΠ-ΠΠ£ΠΡ (ΠΠΎΡΠΊΠ²Π° 2009, 2010), Π‘ΠΈΠΌΠΏΠΎΠ·ΠΈΡΠΌΠ°Ρ «Π‘ΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½Π°Ρ Ρ ΠΈΠΌΠΈΡΠ΅ΡΠΊΠ°Ρ ΡΠΈΠ·ΠΈΠΊΠ°» (Π’ΡΠ°ΠΏΡΠ΅ 2010 ΠΈ 2011), 5-ΠΉ ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΠΎΠΉ ΠΊΠΎΠ½ΡΠ΅ΡΠ΅Π½ΡΠΈΠΈ «ΠΠ°ΡΠ°Π»Π»Π΅Π»ΡΠ½ΡΠ΅ Π²ΡΡΠΈΡΠ»ΠΈΡΠ΅Π»ΡΠ½ΡΠ΅ ΡΠ΅Ρ Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ (ΠΠ°ΠΠ’)» (ΠΠΎΡΠΊΠ²Π° 2011), 26-ΠΉ Π·ΠΈΠΌΠ½Π΅ΠΉ ΡΠΊΠΎΠ»Π΅ ΡΠ΅ΠΎΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Ρ ΠΈΠΌΠΈΠΈ.
Π€ΠΈΠ½Π»ΡΠ½Π΄ΠΈΡ 2010), 19-ΠΉ ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΠΎΠΉ ΠΊΠΎΠ½ΡΠ΅ΡΠ΅Π½ΡΠΈΠΈ «ΠΠΎΠ²ΡΠ΅ Π³ΠΎΡΠΈΠ·ΠΎΠ½ΡΡ Π² ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡΡ Π²ΠΎΠ΄ΠΎΡΠΎΠ΄Π½ΡΡ ΡΠ²ΡΠ·Π΅ΠΉ» (ΠΠ΅ΡΠΌΠ°Π½ΠΈΡ 2011).
Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΎΠΏΡΠ±Π»ΠΈΠΊΠΎΠ²Π°Π½Ρ Π² 11 ΠΏΠ΅ΡΠ°ΡΠ½ΡΡ ΠΈΠ·Π΄Π°Π½ΠΈΡΡ , Π² ΡΠΎΠΌ ΡΠΈΡΠ»Π΅ Π² 6 ΡΡΠ°ΡΡΡΡ Π² ΡΠ΅ΡΠ΅Π½Π·ΠΈΡΡΠ΅ΠΌΡΡ Π½Π°ΡΡΠ½ΡΡ ΠΆΡΡΠ½Π°Π»Π°Ρ , Π²Ρ ΠΎΠ΄ΡΡΠΈΡ Π² ΠΏΠ΅ΡΠ΅ΡΠ΅Π½Ρ ΠΆΡΡΠ½Π°Π»ΠΎΠ² ΠΠΠ Π Π€ ΠΈ Π² 5 ΡΠ΅Π·ΠΈΡΠ°Ρ Π΄ΠΎΠΊΠ»Π°Π΄ΠΎΠ² Π½Π° ΠΊΠΎΠ½ΡΠ΅ΡΠ΅Π½ΡΠΈΡΡ .
ΠΡΠ²ΠΎΠ΄Ρ.
1. Π‘ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ Π½ΠΎΠ²ΠΎΠΉ ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΠΈ Π°Π»Π³ΠΎΡΠΈΡΠΌΠΎΠ² ΠΌΠ΅ΡΠΎΠ΄Π° ΠΠ/ΠΠ Π² Π²Π°ΡΠΈΠ°Π½ΡΠ΅ ΠΊΠΎΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎ-ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΡΡ ΡΡΠ°Π³ΠΌΠ΅Π½ΡΠΎΠ² Π² ΠΏΡΠΎΠ³ΡΠ°ΠΌΠΌΠ½ΠΎΠΌ ΠΏΠ°ΠΊΠ΅ΡΠ΅ GAMES S (US) ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½Ρ ΡΠ°ΡΡΠ΅ΡΡ ΡΠ²ΠΎΠΉΡΡΠ² ΡΡΠ΄Π° Π±ΠΈΠΎΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΡΡ ΡΠΈΡΡΠ΅ΠΌ ΠΈ ΠΏΠΎΠΊΠ°Π·Π°Π½Π° ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΠΈ Π½Π° ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ ΡΡΠΏΠ΅ΡΠΊΠΎΠΌΠΏΡΡΡΠ΅ΡΠ°Ρ .
2. Π‘ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ Π΄Π²ΡΡ ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ Π²Π°ΡΠΈΠ°Π½ΡΠΎΠ² ΠΌΠ΅ΡΠΎΠ΄Π° ΠΠ/ΠΠ (ΠΊΠΎΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎ-ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ ΡΡΠ°Π³ΠΌΠ΅Π½ΡΠΎΠ² ΠΈ Π²Π½Π΅Π΄ΡΡΠ½Π½ΠΎΠ³ΠΎ ΠΊΠ»Π°ΡΡΠ΅ΡΠ°) ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ, ΡΡΠΎ ΡΠ΅Π°ΠΊΡΠΈΡ Π³ΠΈΠ΄ΡΠΎΠ»ΠΈΠ·Π° ΡΠΈΠΊΠ»ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π³ΡΠ°Π½ΠΎΠ·ΠΈΠ½ΠΌΠΎΠ½ΠΎΡΠΎΡΡΠ°ΡΠ° Π² Π²ΠΎΠ΄Π½ΠΎΠΌ ΡΠ°ΡΡΠ²ΠΎΡΠ΅ ΠΏΡΠΎΡΠ΅ΠΊΠ°Π΅Ρ ΠΏΠΎ Π°ΡΡΠΎΡΠΈΠ°ΡΠΈΠ²Π½ΠΎΠΌΡ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΡ Ρ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΠΈΠ½ΡΠ΅ΡΠΌΠ΅Π΄ΠΈΠ°ΡΠ° Ρ ΠΏΠ΅Π½ΡΠ°ΠΊΠΎΠΎΡΠ΄ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΡΠΌ ΡΠΎΡΡΠΎΡΠΎΠΌ.
3. ΠΠ²ΡΠΌΡ ΡΠ°Π·Π»ΠΈΡΠ½ΡΠΌΠΈ ΠΌΠ΅ΡΠΎΠ΄Π°ΠΌΠΈ ΠΠ/ΠΠ ΠΏΠΎΠ΄ΡΠ²Π΅ΡΠΆΠ΄Π΅Π½Π° ΡΡΠ°Π±ΠΈΠ»ΡΠ½ΠΎΡΡΡ ΡΠ΅ΡΡΠ°ΡΠ΄ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΈΠ½ΡΠ΅ΡΠΌΠ΅Π΄ΠΈΠ°ΡΠ° ΡΡΠ°Π΄ΠΈΠΈ Π°ΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠ΅Π°ΠΊΡΠΈΠΈ Π³ΠΈΠ΄ΡΠΎΠ»ΠΈΠ·Π° Π°ΡΠ΅ΡΠΈΠ»Ρ ΠΎΠ»ΠΈΠ½Π° Π² Π°ΠΊΡΠΈΠ²Π½ΠΎΠΌ ΡΠ΅Π½ΡΡΠ΅ Π°ΡΠ΅ΡΠΈΠ»Ρ ΠΎΠ»ΠΈΠ½ΡΡΡΠ΅ΡΠ°Π·Ρ. ΠΠΎΠ΄ΡΠ²Π΅ΡΠΆΠ΄Π΅Π½ΠΎ, ΡΡΠΎ Π΄Π°Π½Π½Π°Ρ ΡΠ΅Π°ΠΊΡΠΈΡ ΠΏΡΠΎΡ ΠΎΠ΄ΠΈΡ ΠΏΠΎ ΠΎΠ΄Π½ΠΎΠΏΡΠΎΡΠΎΠ½Π½ΠΎΠΌΡ ΠΌΠ΅Ρ Π°Π½ΠΈΠ·ΠΌΡ.
4. ΠΡΠ΅Π΄Π»ΠΎΠΆΠ΅Π½Ρ ΡΡΠ΅Π½Π°ΡΠΈΠΈ ΡΠ΅Π°ΠΊΡΠΈΠΈ Π΄Π΅ΠΊΠ°ΡΠ±ΠΎΠΊΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π·Π΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ»ΡΠΎΡΠ΅ΡΡΠ΅Π½ΡΠ½ΠΎΠ³ΠΎ Π±Π΅Π»ΠΊΠ° Ρ ΡΡΠ΅ΡΠΎΠΌ ΠΏΠ΅ΡΠ΅Π½ΠΎΡΠΎΠΌ ΡΠ»Π΅ΠΊΡΡΠΎΠ½Π° Ρ Π°Π½ΠΈΠΎΠ½Π° Glu222 Π½Π° Ρ ΡΠΎΠΌΠΎΡΠΎΡ Ρ ΡΡΠ°ΡΡΠΈΠ΅ΠΌ Π²ΡΡΠΎΠΊΠΎ-Π»Π΅ΠΆΠ°ΡΠΈΡ Π²ΠΎΠ·Π±ΡΠΆΠ΄Π΅Π½Π½ΡΡ ΡΠΎΡΡΠΎΡΠ½ΠΈΠΉ. s.
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